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Influenza Virus Z-RNAs Induce ZBP1-Mediated Necroptosis
Influenza A virus (IAV) is a lytic RNA virus that triggers receptor-interacting serine/threonine-protein kinase 3 (RIPK3)-mediated pathways of apoptosis and mixed lineage kinase domain-like pseudokinase (MLKL)-dependent necroptosis in infected cells. ZBP1 initiates RIPK3-driven cell death by sensing...
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| Veröffentlicht in: | Cell |
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| Hauptverfasser: | , , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7153753/ https://ncbi.nlm.nih.gov/pubmed/32200799 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2020.02.050 |
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