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Signal peptide peptidases: A family of intramembrane-cleaving proteases that cleave type 2 transmembrane proteins

Five genes encode the five human signal peptide peptidases (SPPs), which are intramembrane-cleaving aspartyl proteases (aspartyl I-CLiPs). SPPs have been conserved through evolution with family members found in higher eukaryotes, fungi, protozoa, arachea, and plants. SPPs are related to the presenil...

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Pubblicato in:Semin Cell Dev Biol
Autori principali: Golde, Todd E., Wolfe, Michael S., Greenbaum, Doron C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6701170/
https://ncbi.nlm.nih.gov/pubmed/19429495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcdb.2009.02.003
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