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Intramembrane Proteolysis by Signal Peptide Peptidases: A Comparative Discussion of GXGD-type Aspartyl Proteases

Intramembrane-cleaving proteases are required for reverse signaling and membrane protein degradation. A major class of these proteases is represented by the GXGD-type aspartyl proteases. GXGD describes a novel signature sequence that distinguishes these proteases from conventional aspartyl proteases...

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Autors principals: Fluhrer, Regina, Steiner, Harald, Haass, Christian
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2682845/
https://ncbi.nlm.nih.gov/pubmed/19189970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R800040200
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