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Engineered Dendritic Cell-Directed Concurrent Activation of Multiple T cell Inhibitory Pathways Induces Robust Immune Tolerance

Inhibitory/repressor-receptors are upregulated significantly on activated T cells, and have been the molecules of attention as targets for inducing immune tolerance. Induction of effective antigen specific tolerance depends on concurrent engagement of the TCR and one or more of these inhibitory rece...

詳細記述

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書誌詳細
出版年:Sci Rep
主要な著者: Gudi, Radhika R., Karumuthil-Melethil, Subha, Perez, Nicolas, Li, Gongbo, Vasu, Chenthamarakshan
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6700167/
https://ncbi.nlm.nih.gov/pubmed/31427630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-48464-y
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