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Engineered Dendritic Cell-Directed Concurrent Activation of Multiple T cell Inhibitory Pathways Induces Robust Immune Tolerance

Inhibitory/repressor-receptors are upregulated significantly on activated T cells, and have been the molecules of attention as targets for inducing immune tolerance. Induction of effective antigen specific tolerance depends on concurrent engagement of the TCR and one or more of these inhibitory rece...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Gudi, Radhika R., Karumuthil-Melethil, Subha, Perez, Nicolas, Li, Gongbo, Vasu, Chenthamarakshan
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6700167/
https://ncbi.nlm.nih.gov/pubmed/31427630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-48464-y
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