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Engineered Dendritic Cell-Directed Concurrent Activation of Multiple T cell Inhibitory Pathways Induces Robust Immune Tolerance

Inhibitory/repressor-receptors are upregulated significantly on activated T cells, and have been the molecules of attention as targets for inducing immune tolerance. Induction of effective antigen specific tolerance depends on concurrent engagement of the TCR and one or more of these inhibitory rece...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Gudi, Radhika R., Karumuthil-Melethil, Subha, Perez, Nicolas, Li, Gongbo, Vasu, Chenthamarakshan
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6700167/
https://ncbi.nlm.nih.gov/pubmed/31427630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-48464-y
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