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Engineered Dendritic Cell-Directed Concurrent Activation of Multiple T cell Inhibitory Pathways Induces Robust Immune Tolerance

Inhibitory/repressor-receptors are upregulated significantly on activated T cells, and have been the molecules of attention as targets for inducing immune tolerance. Induction of effective antigen specific tolerance depends on concurrent engagement of the TCR and one or more of these inhibitory rece...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Gudi, Radhika R., Karumuthil-Melethil, Subha, Perez, Nicolas, Li, Gongbo, Vasu, Chenthamarakshan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2019
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6700167/
https://ncbi.nlm.nih.gov/pubmed/31427630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-48464-y
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