Influence of geometric isomerism on the binding of platinum anticancer agents with phospholipids

Reported herein is a detailed NMR and DFT study of the interaction of the (15)N-labelled dinuclear platinum anticancer compound [{cis-PtCl(NH(3))(2)}(2){μ-H(2)N(CH(2))(6)NH(2)}](2+) ((15)N-1, 1,1/c,c) with 1,2-dihexanoyl-sn-glycero-3-phosphate (DHPA), as a comparison with an earlier study of the int...

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Bibliografiska uppgifter
I publikationen:Dalton Trans
Huvudupphovsmän: Gorle, Anil Kumar, Zhang, Junyong, Berners-Price, Susan J., Farrell, Nicholas P.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2019
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6699998/
https://ncbi.nlm.nih.gov/pubmed/31070627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9dt00753a
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