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Influence of geometric isomerism on the binding of platinum anticancer agents with phospholipids
Reported herein is a detailed NMR and DFT study of the interaction of the (15)N-labelled dinuclear platinum anticancer compound [{cis-PtCl(NH(3))(2)}(2){μ-H(2)N(CH(2))(6)NH(2)}](2+) ((15)N-1, 1,1/c,c) with 1,2-dihexanoyl-sn-glycero-3-phosphate (DHPA), as a comparison with an earlier study of the int...
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| Published in: | Dalton Trans |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2019
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6699998/ https://ncbi.nlm.nih.gov/pubmed/31070627 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9dt00753a |
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