Absinthin, an agonist of the bitter taste receptor hTAS2R46, uncovers an ER-to-mitochondria Ca(2+)–shuttling event

Type 2 taste receptors (TAS2R) are G protein–coupled receptors first described in the gustatory system, but have also been shown to have extraoral localizations, including airway smooth muscle (ASM) cells, in which TAS2R have been reported to induce relaxation. TAS2R46 is an unexplored subtype that...

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Bibliografske podrobnosti
izdano v:J Biol Chem
Main Authors: Talmon, Maria, Rossi, Silvia, Lim, Dmitry, Pollastro, Federica, Palattella, Gioele, Ruffinatti, Federico A., Marotta, Patrizia, Boldorini, Renzo, Genazzani, Armando A., Fresu, Luigia G.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2019
Teme:
Signal Transduction
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6699840/
https://ncbi.nlm.nih.gov/pubmed/31248983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.007763
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