Absinthin, an agonist of the bitter taste receptor hTAS2R46, uncovers an ER-to-mitochondria Ca(2+)–shuttling event

Type 2 taste receptors (TAS2R) are G protein–coupled receptors first described in the gustatory system, but have also been shown to have extraoral localizations, including airway smooth muscle (ASM) cells, in which TAS2R have been reported to induce relaxation. TAS2R46 is an unexplored subtype that...

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Библиографические подробности
Опубликовано в: :J Biol Chem
Главные авторы: Talmon, Maria, Rossi, Silvia, Lim, Dmitry, Pollastro, Federica, Palattella, Gioele, Ruffinatti, Federico A., Marotta, Patrizia, Boldorini, Renzo, Genazzani, Armando A., Fresu, Luigia G.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2019
Предметы:
Signal Transduction
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6699840/
https://ncbi.nlm.nih.gov/pubmed/31248983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.007763
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