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The Drosophila Hedgehog receptor component Interference hedgehog (Ihog) mediates cell–cell interactions through trans-homophilic binding

Hedgehog (Hh) signaling is crucial for establishing complex cellular patterns in embryonic tissues and maintaining homeostasis in adult organs. In Drosophila, Interference hedgehog (Ihog) or its close paralogue Brother of Ihog (Boi) forms a receptor complex with Patched to mediate intracellular Hh s...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Main Authors: Wu, Xuefeng, Zhang, Ya, Chuang, Kun-Han, Cai, Xudong, Ajaz, Humna, Zheng, Xiaoyan
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6699836/
https://ncbi.nlm.nih.gov/pubmed/31209108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.008744
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