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The Drosophila Hedgehog receptor component Interference hedgehog (Ihog) mediates cell–cell interactions through trans-homophilic binding

Hedgehog (Hh) signaling is crucial for establishing complex cellular patterns in embryonic tissues and maintaining homeostasis in adult organs. In Drosophila, Interference hedgehog (Ihog) or its close paralogue Brother of Ihog (Boi) forms a receptor complex with Patched to mediate intracellular Hh s...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Wu, Xuefeng, Zhang, Ya, Chuang, Kun-Han, Cai, Xudong, Ajaz, Humna, Zheng, Xiaoyan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6699836/
https://ncbi.nlm.nih.gov/pubmed/31209108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.008744
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