Competitive coordination of the dual roles of the Hedgehog co-receptor in homophilic adhesion and signal reception

Hedgehog (Hh) signaling patterns embryonic tissues and contributes to homeostasis in adults. In Drosophila, Hh transport and signaling are thought to occur along a specialized class of actin-rich filopodia, termed cytonemes. Here, we report that Interference hedgehog (Ihog) not only forms a Hh recep...

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Udgivet i:eLife
Main Authors: Yang, Shu, Zhang, Ya, Yang, Chuxuan, Wu, Xuefeng, El Oud, Sarah Maria, Chen, Rongfang, Cai, Xudong, Wu, Xufeng S, Lan, Ganhui, Zheng, Xiaoyan
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2021
Fag:
Developmental Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8131103/
https://ncbi.nlm.nih.gov/pubmed/34003115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.65770
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