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The mode of Hedgehog binding to Ihog homologs is not conserved across different phyla

Hedgehog (Hh) proteins specify tissue pattern in metazoan embryos by forming gradients that emanate from discrete sites of expression and elicit concentration-dependent cellular differentiation or proliferation responses1,2. Cellular responses to Hh and the movement of Hh through tissues are both pr...

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Detalhes bibliográficos
Main Authors: McLellan, Jason S., Zheng, Xiaoyan, Hauk, Glenn, Ghirlando, Rodolfo, Beachy, Philip A., Leahy, Daniel J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2679680/
https://ncbi.nlm.nih.gov/pubmed/18794898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07358
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