Hedgehog mediated degradation of Ihog adhesion proteins modulates cell segregation in Drosophila wing imaginal discs

The Drosophila Hedgehog receptor functions to regulate the essential downstream pathway component, Smoothened, and to limit the range of signaling by sequestering Hedgehog protein signal within imaginal disc epithelium. Hedgehog receptor function requires both Patched and Ihog activity, the latter i...

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Bibliografiset tiedot
Julkaisussa:Nat Commun
Päätekijät: Hsia, Elaine Y. C., Zhang, Ya, Tran, Hai Son, Lim, Agnes, Chou, Ya-Hui, Lan, Ganhui, Beachy, Philip A., Zheng, Xiaoyan
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2017
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5668237/
https://ncbi.nlm.nih.gov/pubmed/29097673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01364-z
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