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Epigenetic Regulation by Endogenous Metabolite Pharmacology

Altered metabolite levels are now well-established to drive epigenetic changes in development and disease. However, in many cases the specific protein–metabolite interactions that underlie this process remain enigmatic. In this review, we make the case that this fundamental missing information may b...

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Detalhes bibliográficos
Publicado no:Curr Opin Chem Biol
Main Authors: Kulkarni, Rhushikesh A., Montgomery, David C, Meier, Jordan L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6698396/
https://ncbi.nlm.nih.gov/pubmed/30884380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpa.2019.02.002
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