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Chemical Cryptology of Cancer’s Histone Code
Somatic mutations in non-Hodgkin’s lymphoma frequently activate EZH2, a protein methyltransferase responsible for H3K27 trimethylation. In this issue of Chemistry and Biology, Bradley and coworkers describe a new set of EZH2 inhibitors amenable to probing the targetable role of H3K27 trimethylation...
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| Publicado no: | Chem Biol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6320250/ https://ncbi.nlm.nih.gov/pubmed/25457120 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2014.11.003 |
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