Global Profiling of Acetyltransferase Feedback Regulation

Lysine acetyltransferases (KATs) are key mediators of cell signaling. Methods capable of providing new insights into their regulation thus constitute an important goal. Here we report an optimized platform for profiling KAT-ligand interactions in complex proteomes using inhibitor-functionalized capt...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Montgomery, David C., Garlick, Julie, Kulkarni, Rhushikesh A., Kennedy, Steven, Allali-Hassani, Abdellah, Kuo, Yin-Ming, Andrews, Andrew J., Wu, Hong, Vedadi, Masoud, Meier, Jordan L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6320254/
https://ncbi.nlm.nih.gov/pubmed/27149119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b03036
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