Global Profiling of Acetyltransferase Feedback Regulation

Lysine acetyltransferases (KATs) are key mediators of cell signaling. Methods capable of providing new insights into their regulation thus constitute an important goal. Here we report an optimized platform for profiling KAT-ligand interactions in complex proteomes using inhibitor-functionalized capt...

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Pubblicato in:J Am Chem Soc
Autori principali: Montgomery, David C., Garlick, Julie, Kulkarni, Rhushikesh A., Kennedy, Steven, Allali-Hassani, Abdellah, Kuo, Yin-Ming, Andrews, Andrew J., Wu, Hong, Vedadi, Masoud, Meier, Jordan L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6320254/
https://ncbi.nlm.nih.gov/pubmed/27149119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b03036
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