Global Profiling of Acetyltransferase Feedback Regulation

Lysine acetyltransferases (KATs) are key mediators of cell signaling. Methods capable of providing new insights into their regulation thus constitute an important goal. Here we report an optimized platform for profiling KAT-ligand interactions in complex proteomes using inhibitor-functionalized capt...

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Udgivet i:J Am Chem Soc
Main Authors: Montgomery, David C., Garlick, Julie, Kulkarni, Rhushikesh A., Kennedy, Steven, Allali-Hassani, Abdellah, Kuo, Yin-Ming, Andrews, Andrew J., Wu, Hong, Vedadi, Masoud, Meier, Jordan L.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6320254/
https://ncbi.nlm.nih.gov/pubmed/27149119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b03036
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