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Ortho-Methylarylamines as Time-Dependent Inhibitors of Cytochrome P450 1A1 Enzyme
Members of the cytochrome P450 1A family metabolize many procarcinogens such as polycyclic aromatic hydrocarbons and heterocyclic amines. Inactivation of these enzymes is a prerequisite for cancer prevention and treatment in certain cases. Mechanism-based inhibition (time and co-factor dependent) is...
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| Udgivet i: | Drug Metab Lett |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6697106/ https://ncbi.nlm.nih.gov/pubmed/28000546 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1872312810666161220155226 |
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