Loss of adaptive myelination contributes to methotrexate chemotherapy-related cognitive impairment

Activity-dependent myelination is thought to contribute to adaptive neurological function. However, the mechanisms by which activity regulates myelination and the extent to which myelin plasticity contributes to non-motor cognitive functions remain incompletely understood. Using a mouse model of che...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Neuron
Prif Awduron: Geraghty, Anna C, Gibson, Erin M, Ghanem, Reem A., Greene, Jacob J., Ocampo, Alfonso, Goldstein, Andrea K, Ni, Lijun, Yang, Tao, Marton, Rebecca M, Paşca, Sergiu P, Greenberg, Michael E, Longo, Frank M, Monje, Michelle
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2019
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6697075/
https://ncbi.nlm.nih.gov/pubmed/31122677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2019.04.032
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