Loss of adaptive myelination contributes to methotrexate chemotherapy-related cognitive impairment

Activity-dependent myelination is thought to contribute to adaptive neurological function. However, the mechanisms by which activity regulates myelination and the extent to which myelin plasticity contributes to non-motor cognitive functions remain incompletely understood. Using a mouse model of che...

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Publicat a:Neuron
Autors principals: Geraghty, Anna C, Gibson, Erin M, Ghanem, Reem A., Greene, Jacob J., Ocampo, Alfonso, Goldstein, Andrea K, Ni, Lijun, Yang, Tao, Marton, Rebecca M, Paşca, Sergiu P, Greenberg, Michael E, Longo, Frank M, Monje, Michelle
Format: Artigo
Idioma:Inglês
Publicat: 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6697075/
https://ncbi.nlm.nih.gov/pubmed/31122677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2019.04.032
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