Loss of adaptive myelination contributes to methotrexate chemotherapy-related cognitive impairment

Activity-dependent myelination is thought to contribute to adaptive neurological function. However, the mechanisms by which activity regulates myelination and the extent to which myelin plasticity contributes to non-motor cognitive functions remain incompletely understood. Using a mouse model of che...

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Detalhes bibliográficos
Publicado no:Neuron
Main Authors: Geraghty, Anna C, Gibson, Erin M, Ghanem, Reem A., Greene, Jacob J., Ocampo, Alfonso, Goldstein, Andrea K, Ni, Lijun, Yang, Tao, Marton, Rebecca M, Paşca, Sergiu P, Greenberg, Michael E, Longo, Frank M, Monje, Michelle
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6697075/
https://ncbi.nlm.nih.gov/pubmed/31122677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2019.04.032
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