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Methotrexate Neurotoxicity Is Related to Epigenetic Modification of the Myelination Process

With the improvement of the survival rate of acute lymphoblastic leukemia (ALL) in children, some children ALL survivors reveal inferior intellectual and cognition outcome. Methotrexate (MTX), while serving as an essential component in ALL treatment, has been reported to be related to various neurol...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Chen, Yu-Chieh, Sheen, Jiunn-Ming, Wang, Su-Chen, Hsu, Mei-Hsin, Hsiao, Chih-Cheng, Chang, Kow-Aung, Huang, Li-Tung
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8267729/
https://ncbi.nlm.nih.gov/pubmed/34201550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22136718
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