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Methotrexate Neurotoxicity Is Related to Epigenetic Modification of the Myelination Process

With the improvement of the survival rate of acute lymphoblastic leukemia (ALL) in children, some children ALL survivors reveal inferior intellectual and cognition outcome. Methotrexate (MTX), while serving as an essential component in ALL treatment, has been reported to be related to various neurol...

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Detalles Bibliográficos
Publicado en:Int J Mol Sci
Autores principales: Chen, Yu-Chieh, Sheen, Jiunn-Ming, Wang, Su-Chen, Hsu, Mei-Hsin, Hsiao, Chih-Cheng, Chang, Kow-Aung, Huang, Li-Tung
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8267729/
https://ncbi.nlm.nih.gov/pubmed/34201550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22136718
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