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Methotrexate Neurotoxicity Is Related to Epigenetic Modification of the Myelination Process

With the improvement of the survival rate of acute lymphoblastic leukemia (ALL) in children, some children ALL survivors reveal inferior intellectual and cognition outcome. Methotrexate (MTX), while serving as an essential component in ALL treatment, has been reported to be related to various neurol...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Chen, Yu-Chieh, Sheen, Jiunn-Ming, Wang, Su-Chen, Hsu, Mei-Hsin, Hsiao, Chih-Cheng, Chang, Kow-Aung, Huang, Li-Tung
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8267729/
https://ncbi.nlm.nih.gov/pubmed/34201550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22136718
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