Neuronal Activity Promotes Oligodendrogenesis and Adaptive Myelination in the Mammalian Brain

Myelination of the central nervous system requires the generation of functionally mature oligodendrocytes from oligodendrocyte precursor cells (OPCs). Electrically active neurons may influence OPC function and selectively instruct myelination of an active neural circuit. In this work, we use optogen...

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Autors principals: Gibson, Erin M., Purger, David, Mount, Christopher W., Goldstein, Andrea K., Lin, Grant L., Wood, Lauren S., Inema, Ingrid, Miller, Sarah E., Bieri, Gregor, Zuchero, J. Bradley, Barres, Ben A., Woo, Pamelyn J., Vogel, Hannes, Monje, Michelle
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4096908/
https://ncbi.nlm.nih.gov/pubmed/24727982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1252304
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