Methotrexate chemotherapy induces persistent tri-glial dysregulation that underlies chemotherapy-related cognitive impairment

Chemotherapy results in a frequent yet poorly understood syndrome of long-term neurological deficits. Neural precursor cell and white matter dysfunction are thought to contribute to this debilitating syndrome. Here, we demonstrate persistent depletion of oligodendrocyte lineage cells in humans who r...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Cell
Main Authors: Gibson, Erin M., Nagaraja, Surya, Ocampo, Alfonso, Tam, Lydia T., Wood, Lauren S., Pallegar, Praveen N., Greene, Jacob J., Geraghty, Anna C., Goldstein, Andrea K., Ni, Lijun, Woo, Pamelyn J., Barres, Ben A., Liddelow, Shane, Vogel, Hannes, Monje, Michelle
Formato: Artigo
Idioma:Inglês
Publicado: 2018
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6329664/
https://ncbi.nlm.nih.gov/pubmed/30528430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.10.049
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares