Methotrexate chemotherapy induces persistent tri-glial dysregulation that underlies chemotherapy-related cognitive impairment

Chemotherapy results in a frequent yet poorly understood syndrome of long-term neurological deficits. Neural precursor cell and white matter dysfunction are thought to contribute to this debilitating syndrome. Here, we demonstrate persistent depletion of oligodendrocyte lineage cells in humans who r...

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Bibliografski detalji
Izdano u:Cell
Glavni autori: Gibson, Erin M., Nagaraja, Surya, Ocampo, Alfonso, Tam, Lydia T., Wood, Lauren S., Pallegar, Praveen N., Greene, Jacob J., Geraghty, Anna C., Goldstein, Andrea K., Ni, Lijun, Woo, Pamelyn J., Barres, Ben A., Liddelow, Shane, Vogel, Hannes, Monje, Michelle
Format: Artigo
Jezik:Inglês
Izdano: 2018
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6329664/
https://ncbi.nlm.nih.gov/pubmed/30528430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.10.049
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