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HGG-22. TARGETING NEURONAL ACTIVITY-REGULATED NEUROLIGIN-3 DEPENDENCY FOR HIGH-GRADE GLIOMA THERAPY

Neuronal activity promotes high-grade glioma (HGG) growth. An important mechanism mediating this neural regulation of brain cancer is activity-dependent cleavage and secretion of the synaptic molecule and glioma mitogen neuroligin-3 (Nlgn3), but the therapeutic potential of targeting Nlgn3 in glioma...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Venkatesh, Humsa S, Tam, Lydia T, Woo, Pamelyn J, Monje, Michelle
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5475067/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox083.111
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