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HGG-22. TARGETING NEURONAL ACTIVITY-REGULATED NEUROLIGIN-3 DEPENDENCY FOR HIGH-GRADE GLIOMA THERAPY
Neuronal activity promotes high-grade glioma (HGG) growth. An important mechanism mediating this neural regulation of brain cancer is activity-dependent cleavage and secretion of the synaptic molecule and glioma mitogen neuroligin-3 (Nlgn3), but the therapeutic potential of targeting Nlgn3 in glioma...
Sparad:
I publikationen: | Neuro Oncol |
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Huvudupphovsmän: | , , , |
Materialtyp: | Artigo |
Språk: | Inglês |
Publicerad: |
Oxford University Press
2017
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Ämnen: | |
Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5475067/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox083.111 |
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