A polymorphism in the lysyl oxidase propeptide domain accelerates carcinogen-induced cancer

The propeptide (LOX-PP) domain of the lysyl oxidase proenzyme was shown to inhibit the transformed phenotype of breast, lung and pancreatic cells in culture and the formation of Her2/neu-driven breast cancer in a xenograft model. A single nucleotide polymorphism (SNP, rs1800449) positioned in a high...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Carcinogenesis
Egile Nagusiak: de la Cueva, Ana, Emmerling, Michael, Lim, Sarah L, Yang, Shi, Trackman, Philip C, Sonenshein, Gail E, Kirsch, Kathrin H
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2018
Gaiak:
Carcinogenesis
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6692853/
https://ncbi.nlm.nih.gov/pubmed/29579155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgy045
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