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A polymorphism in the lysyl oxidase propeptide domain accelerates carcinogen-induced cancer
The propeptide (LOX-PP) domain of the lysyl oxidase proenzyme was shown to inhibit the transformed phenotype of breast, lung and pancreatic cells in culture and the formation of Her2/neu-driven breast cancer in a xenograft model. A single nucleotide polymorphism (SNP, rs1800449) positioned in a high...
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| Veröffentlicht in: | Carcinogenesis |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6692853/ https://ncbi.nlm.nih.gov/pubmed/29579155 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgy045 |
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