Opioid‐sparing effects of cannabinoids on morphine analgesia: participation of CB(1) and CB(2) receptors

BACKGROUND AND PURPOSE: Much of the opioid epidemic arose from abuse of prescription opioid drugs. This study sought to determine if the combination of a cannabinoid with an opioid could produce additive or synergistic effects on pain, allowing reduction in the opioid dose needed for maximal analges...

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Vydáno v:Br J Pharmacol
Hlavní autoři: Chen, Xiaohong, Cowan, Alan, Inan, Saadet, Geller, Ellen B., Meissler, Joseph J., Rawls, Scott M., Tallarida, Ronald J., Tallarida, Christopher S., Watson, Mia N., Adler, Martin W., Eisenstein, Toby K.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2019
Témata:
Research Papers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6692585/
https://ncbi.nlm.nih.gov/pubmed/31218677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14769
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