Coadministration of Chemokine Receptor Antagonists with Morphine Potentiates Morphine’s Analgesic Effect on Incisional Pain in Rats

Crossdesensitization between opioid and chemokine receptors and involvement of chemokines in pain modulation are well established. We investigated if coadministration of chemokine receptor antagonists (CRAs) with morphine would enhance the analgesic potency of morphine on incisional pain in rats. An...

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Detalhes bibliográficos
Publicado no:J Pharmacol Exp Ther
Main Authors: Inan, Saadet, Eisenstein, Toby K., Watson, Mia N., Doura, Menahem, Meissler, Joseph J., Tallarida, Christopher S., Chen, Xiaohong, Geller, Ellen B., Rawls, Scott M., Cowan, Alan, Adler, Martin W.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2018
Assuntos:
Behavioral Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6226546/
https://ncbi.nlm.nih.gov/pubmed/30249618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.118.252890
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