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A CB2-Selective Cannabinoid Suppresses T-cell Activities and Increases Tregs and IL-10

We have previously shown that agonists selective for the cannabinoid receptor 2 (CB2), including O-1966, inhibit the Mixed Lymphocyte Reaction (MLR), an in vitro correlate of organ graft rejection, predominantly through effects on T-cells. Current studies explored the mechanism of this immunosuppres...

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Detalhes bibliográficos
Publicado no:J Neuroimmune Pharmacol
Main Authors: Robinson, Rebecca H., Meissler, Joseph J., Fan, Xiaoxuan, Yu, Daohai, Adler, Martin W., Eisenstein, Toby K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4528965/
https://ncbi.nlm.nih.gov/pubmed/25980325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11481-015-9611-3
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