Overcoming EZH2 Inhibitor Resistance by Taxane in PTEN-Mutated Cancer

Rationale: The Polycomb group (PcG) protein EZH2 is implicated in cancer progression due to its frequent overexpression in many cancer types and therefore is a promising therapeutic target. Forkhead box transcription factor-1 (FOXO1) is a tumor suppressor that is often transcriptionally downregulate...

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Dettagli Bibliografici
Pubblicato in:Theranostics
Autori principali: Ma, Linlin, Yan, Yuqian, Bai, Yang, Yang, Yinhui, Pan, Yunqian, Gang, Xiaokun, Karnes, R. Jeffrey, Zhang, Jun, Lv, Qiubo, Wu, Qiang, Huang, Haojie
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ivyspring International Publisher 2019
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6691386/
https://ncbi.nlm.nih.gov/pubmed/31410199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.34700
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