Inhibition of EZH2 by chemo- and radiotherapy agents and small molecule inhibitors induces cell death in castration-resistant prostate cancer

Androgen deprivation therapy is the mainstay of treatment of advanced prostate cancer (PCa). However, a significant portion of patients experience disease relapse and tumors ultimately evolve into castration resistant prostate cancer (CRPC), for which there is no cure in the clinic. The Polycomb pro...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Wu, Changping, Jin, Xin, Yang, Jing, Yang, Yinhui, He, Yundong, Ding, Liya, Pan, Yunqian, Chen, Shuai, Jiang, Jingting, Huang, Haojie
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4823118/
https://ncbi.nlm.nih.gov/pubmed/26657505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6497
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