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Critical Review Evolution of a Dynamic Molecular Switch
Eukaryotic protein kinases (EPKs) regulate almost every biological process and have evolved to be dynamic molecular switches; this is in stark contrast to metabolic enzymes, which have evolved to be efficient catalysts. In particular, the highly conserved active site of every EPK is dynamically and...
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| Veröffentlicht in: | IUBMB Life |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6690480/ https://ncbi.nlm.nih.gov/pubmed/31059206 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/iub.2059 |
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