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Pseudokinases from a structural perspective

The catalytic (C) subunit of PKA was the first protein kinase structure to be solved, and it continues to serve as the prototype for the protein kinase superfamily. In contrast, by comparing many active and inactive kinases, we developed a novel ‘spine’ concept where every active kinase is composed...

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Détails bibliographiques
Publié dans:Biochem Soc Trans
Auteurs principaux: Taylor, Susan S., Shaw, Andrey, Hu, Jiancheng, Meharena, Hiruy S., Kornev, Alexandr
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4399968/
https://ncbi.nlm.nih.gov/pubmed/23863167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20130120
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