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Kinases and Pseudokinases: Lessons from RAF

Protein kinases are thought to mediate their biological effects through their catalytic activity. The large number of pseudokinases in the kinome and an increasing appreciation that they have critical roles in signaling pathways, however, suggest that catalyzing protein phosphorylation may not be th...

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Autori principali: Shaw, Andrey S., Kornev, Alexandr P., Hu, Jiancheng, Ahuja, Lalima G., Taylor, Susan S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3993607/
https://ncbi.nlm.nih.gov/pubmed/24567368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00057-14
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