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Kinases and Pseudokinases: Lessons from RAF

Protein kinases are thought to mediate their biological effects through their catalytic activity. The large number of pseudokinases in the kinome and an increasing appreciation that they have critical roles in signaling pathways, however, suggest that catalyzing protein phosphorylation may not be th...

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Detalhes bibliográficos
Main Authors: Shaw, Andrey S., Kornev, Alexandr P., Hu, Jiancheng, Ahuja, Lalima G., Taylor, Susan S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3993607/
https://ncbi.nlm.nih.gov/pubmed/24567368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00057-14
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