Synthesis and characterization of a long-acting emtricitabine prodrug nanoformulation

PURPOSE: A palmitoylated prodrug of emtricitabine (FTC) was synthesized to extend the drug’s half-life, antiretroviral activities and biodistribution. METHODS: A modified FTC prodrug (MFTC) was synthesized by palmitoyl chloride esterification. MFTC’s chemical structure was evaluated by nuclear magne...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Int J Nanomedicine
Autors principals: Ibrahim, Ibrahim M, Bade, Aditya N, Lin, Zhiyi, Soni, Dhruvkumar, Wojtkiewicz, Melinda, Dyavar Shetty, Bhagya Laxmi, Gautam, Nagsen, McMillan, JoEllyn M, Alnouti, Yazen, Edagwa, Benson J, Gendelman, Howard E
Format: Artigo
Idioma:Inglês
Publicat: Dove 2019
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6689761/
https://ncbi.nlm.nih.gov/pubmed/31496683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S215447
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars