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Creation of a Long-Acting Rilpivirine Prodrug Nanoformulation

Antiretroviral therapy requires lifelong daily dosing to attain viral suppression, restore immune function, and improve quality of life. As a treatment alternative, long-acting (LA) antiretrovirals can sustain therapeutic drug concentrations in blood for prolonged time periods. The success of recent...

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Détails bibliographiques
Publié dans:J Control Release
Auteurs principaux: Hilaire, James R., Bade, Aditya N., Sillman, Brady, Gautam, Nagsen, Herskovitz, Jonathan, Shetty, Bhagya Laxmi Dyavar, Wojtkiewicz, Melinda S., Szlachetka, Adam, Lamberty, Ben, Sravanam, Sruthi, Fox, Howard, Alnouti, Yazen, Dash, Prasanta K., McMillan, JoEllyn M., Edagwa, Benson J., Gendelman, Howard E.
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6875695/
https://ncbi.nlm.nih.gov/pubmed/31491432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2019.09.001
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