Creation of a Long-Acting Rilpivirine Prodrug Nanoformulation

Antiretroviral therapy requires lifelong daily dosing to attain viral suppression, restore immune function, and improve quality of life. As a treatment alternative, long-acting (LA) antiretrovirals can sustain therapeutic drug concentrations in blood for prolonged time periods. The success of recent...

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Pubblicato in:J Control Release
Autori principali: Hilaire, James R., Bade, Aditya N., Sillman, Brady, Gautam, Nagsen, Herskovitz, Jonathan, Shetty, Bhagya Laxmi Dyavar, Wojtkiewicz, Melinda S., Szlachetka, Adam, Lamberty, Ben, Sravanam, Sruthi, Fox, Howard, Alnouti, Yazen, Dash, Prasanta K., McMillan, JoEllyn M., Edagwa, Benson J., Gendelman, Howard E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6875695/
https://ncbi.nlm.nih.gov/pubmed/31491432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2019.09.001
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