A Year-Long Extended Release Nanoformulated Cabotegravir Prodrug

Long-acting cabotegravir (CAB) extends antiretroviral drug (ARV) administration from daily to monthly. However, dosing volumes, injection site reactions, and health care oversight are obstacles towards broad usage. The creation of poloxamer-coated hydrophobic and lipophilic CAB prodrugs with control...

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Bibliografski detalji
Izdano u:Nat Mater
Glavni autori: Kulkarni, Tanmay A., Bade, Aditya N., Sillman, Brady, Dyavar Shetty, Bhagya Laxmi, Wojtkiewicz, Melinda S., Gautam, Nagsen, Hilaire, James R., Sravanam, Sruthi, Szlachetka, Adam, Lamberty, Benjamin G., Morsey, Brenda M., Fox, Howard S., Alnouti, Yazen, McMillan, JoEllyn M., Mosley, R. Lee, Meza, Jane, Domanico, Paul L., Yue, Tai-Yuen, Moore, Gary, Edagwa, Benson J., Gendelman, Howard E.
Format: Artigo
Jezik:Inglês
Izdano: 2020
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7384935/
https://ncbi.nlm.nih.gov/pubmed/32341511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41563-020-0674-z
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