A Year-Long Extended Release Nanoformulated Cabotegravir Prodrug

Long-acting cabotegravir (CAB) extends antiretroviral drug (ARV) administration from daily to monthly. However, dosing volumes, injection site reactions, and health care oversight are obstacles towards broad usage. The creation of poloxamer-coated hydrophobic and lipophilic CAB prodrugs with control...

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Detalhes bibliográficos
Publicado no:Nat Mater
Main Authors: Kulkarni, Tanmay A., Bade, Aditya N., Sillman, Brady, Dyavar Shetty, Bhagya Laxmi, Wojtkiewicz, Melinda S., Gautam, Nagsen, Hilaire, James R., Sravanam, Sruthi, Szlachetka, Adam, Lamberty, Benjamin G., Morsey, Brenda M., Fox, Howard S., Alnouti, Yazen, McMillan, JoEllyn M., Mosley, R. Lee, Meza, Jane, Domanico, Paul L., Yue, Tai-Yuen, Moore, Gary, Edagwa, Benson J., Gendelman, Howard E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7384935/
https://ncbi.nlm.nih.gov/pubmed/32341511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41563-020-0674-z
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