A Year-Long Extended Release Nanoformulated Cabotegravir Prodrug

Long-acting cabotegravir (CAB) extends antiretroviral drug (ARV) administration from daily to monthly. However, dosing volumes, injection site reactions, and health care oversight are obstacles towards broad usage. The creation of poloxamer-coated hydrophobic and lipophilic CAB prodrugs with control...

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Bibliografiske detaljer
Udgivet i:Nat Mater
Main Authors: Kulkarni, Tanmay A., Bade, Aditya N., Sillman, Brady, Dyavar Shetty, Bhagya Laxmi, Wojtkiewicz, Melinda S., Gautam, Nagsen, Hilaire, James R., Sravanam, Sruthi, Szlachetka, Adam, Lamberty, Benjamin G., Morsey, Brenda M., Fox, Howard S., Alnouti, Yazen, McMillan, JoEllyn M., Mosley, R. Lee, Meza, Jane, Domanico, Paul L., Yue, Tai-Yuen, Moore, Gary, Edagwa, Benson J., Gendelman, Howard E.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7384935/
https://ncbi.nlm.nih.gov/pubmed/32341511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41563-020-0674-z
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