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Synthesis and Characterization of Long Acting Darunavir Prodrugs

Antiretroviral therapy (ART) has improved the quality of life in patients infected with HIV-1. However, complete viral suppression within anatomical compartments remains unattainable. This is complicated by adverse side effects and poor adherence to lifelong therapy leading to the emergence of viral...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Mol Pharm
Hauptverfasser: Banoub, Mary G., Bade, Aditya N., Lin, Zhiyi, Cobb, Denise, Gautam, Nagsen, Dyavar Shetty, Bhagya Laxmi, Wojtkiewicz, Melinda, Alnouti, Yazen, McMillan, JoEllyn, Gendelman, Howard E., Edagwa, Benson
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7295016/
https://ncbi.nlm.nih.gov/pubmed/31742407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.9b00871
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