Synthesis and characterization of a long-acting emtricitabine prodrug nanoformulation

PURPOSE: A palmitoylated prodrug of emtricitabine (FTC) was synthesized to extend the drug’s half-life, antiretroviral activities and biodistribution. METHODS: A modified FTC prodrug (MFTC) was synthesized by palmitoyl chloride esterification. MFTC’s chemical structure was evaluated by nuclear magne...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Ibrahim, Ibrahim M, Bade, Aditya N, Lin, Zhiyi, Soni, Dhruvkumar, Wojtkiewicz, Melinda, Dyavar Shetty, Bhagya Laxmi, Gautam, Nagsen, McMillan, JoEllyn M, Alnouti, Yazen, Edagwa, Benson J, Gendelman, Howard E
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2019
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6689761/
https://ncbi.nlm.nih.gov/pubmed/31496683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S215447
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados