3’ Uridylation Confers miRNAs With Non-canonical Target Repertoires

Many microRNAs (miRNAs) exist alongside abundant miRNA isoforms (isomiRs), most of which arise from post-maturation sequence modifications, such as 3’ uridylation. However, the ways in which these sequence modifications affect miRNA function remain poorly understood. Here, using human miR-27a in cel...

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Vydáno v:Mol Cell
Hlavní autoři: Yang, Acong, Ros, Xavier Bofill-De, Shao, Tie-Juan, Jiang, Minjie, Li, Katherine, Villanueva, Patricia, Dai, Lisheng, Gu, Shuo
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6688926/
https://ncbi.nlm.nih.gov/pubmed/31178353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.05.014
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