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Novel, abundant Drosha isoforms are deficient in miRNA processing in cancer cells
MicroRNAs (miRNAs) are a class of small noncoding RNAs about 22-nucleotide (nt) in length that collectively regulate more than 60% of coding genes. Aberrant miRNA expression is associated with numerous diseases, including cancer. miRNA biogenesis is licenced by the ribonuclease (RNase) III enzyme Dr...
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| Publicado no: | RNA Biol |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7567492/ https://ncbi.nlm.nih.gov/pubmed/32819190 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2020.1813439 |
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