Novel, abundant Drosha isoforms are deficient in miRNA processing in cancer cells

MicroRNAs (miRNAs) are a class of small noncoding RNAs about 22-nucleotide (nt) in length that collectively regulate more than 60% of coding genes. Aberrant miRNA expression is associated with numerous diseases, including cancer. miRNA biogenesis is licenced by the ribonuclease (RNase) III enzyme Dr...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:RNA Biol
Egile Nagusiak: Dai, Lisheng, Hallmark, Lillian, Bofill De Ros, Xavier, Crouch, Howard, Chen, Sean, Shi, Tony, Yang, Acong, Lian, Chuanjiang, Zhao, Yongmei, Tran, Bao, Gu, Shuo
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Taylor & Francis 2020
Gaiak:
Research Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7567492/
https://ncbi.nlm.nih.gov/pubmed/32819190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2020.1813439
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