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Guidelines for the optimal design of miRNA-based shRNAs
RNA interference (RNAi) is an extremely useful tool for inhibiting gene expression. It can be triggered by transfected synthetic small interfering RNA (siRNA) or by expressed small hairpin RNA (shRNA). The cellular machinery processes the latter into siRNA in vivo. shRNA is preferred or required in...
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| 發表在: | Methods |
|---|---|
| Main Authors: | , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4921303/ https://ncbi.nlm.nih.gov/pubmed/27083402 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2016.04.003 |
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