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Optimized models for design of efficient miR30-based shRNAs

Small hairpin RNAs (shRNAs) became an important research tool in cell biology. Reliable design of these molecules is essential for the needs of large functional genomics projects. To optimize the design of efficient shRNAs, we performed comparative, thermodynamic, and correlation analyses of ~18,000...

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Detalhes bibliográficos
Main Authors: Matveeva, Olga V., Nazipova, Nafisa N., Ogurtsov, Aleksey Y., Shabalina, Svetlana A.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3429853/
https://ncbi.nlm.nih.gov/pubmed/22952469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2012.00163
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