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Sequence characteristics define trade-offs between on-target and genome-wide off-target hybridization of oligoprobes
Off-target oligoprobe’s interaction with partially complementary nucleotide sequences represents a problem for many bio-techniques. The goal of the study was to identify oligoprobe sequence characteristics that control the ratio between on-target and off-target hybridization. To understand the compl...
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| Publié dans: | PLoS One |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6013149/ https://ncbi.nlm.nih.gov/pubmed/29928000 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0199162 |
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