Identification of regions in multiple sequence alignments thermodynamically suitable for targeting by consensus oligonucleotides: application to HIV genome

BACKGROUND: Computer programs for the generation of multiple sequence alignments such as "Clustal W" allow detection of regions that are most conserved among many sequence variants. However, even for regions that are equally conserved, their potential utility as hybridization targets varie...

Full description

Saved in:
Bibliographic Details
Main Authors: Matveeva, Olga V, Foley, Brian T, Nemtsov, Vladimir A, Gesteland, Raymond F, Matsufuji, Senya, Atkins, John F, Ogurtsov, Alexei Y, Shabalina, Svetlana A
Format: Artigo
Language:Inglês
Published: BioMed Central 2004
Subjects:
Methodology Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC419695/
https://ncbi.nlm.nih.gov/pubmed/15115544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-5-44
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items