Identification of regions in multiple sequence alignments thermodynamically suitable for targeting by consensus oligonucleotides: application to HIV genome

BACKGROUND: Computer programs for the generation of multiple sequence alignments such as "Clustal W" allow detection of regions that are most conserved among many sequence variants. However, even for regions that are equally conserved, their potential utility as hybridization targets varie...

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Bibliografische gegevens
Hoofdauteurs: Matveeva, Olga V, Foley, Brian T, Nemtsov, Vladimir A, Gesteland, Raymond F, Matsufuji, Senya, Atkins, John F, Ogurtsov, Alexei Y, Shabalina, Svetlana A
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2004
Onderwerpen:
Methodology Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC419695/
https://ncbi.nlm.nih.gov/pubmed/15115544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-5-44
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