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Identification of regions in multiple sequence alignments thermodynamically suitable for targeting by consensus oligonucleotides: application to HIV genome

BACKGROUND: Computer programs for the generation of multiple sequence alignments such as "Clustal W" allow detection of regions that are most conserved among many sequence variants. However, even for regions that are equally conserved, their potential utility as hybridization targets varies. Mismatc...

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Detaylı Bibliyografya
Yayımlandı:BMC Bioinformatics
Asıl Yazarlar: Matveeva, Olga V, Foley, Brian T, Nemtsov, Vladimir A, Gesteland, Raymond F, Matsufuji, Senya, Atkins, John F, Ogurtsov, Alexei Y, Shabalina, Svetlana A
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BMC 2004
Konular:
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC419695/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15115544/
https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1471-2105-5-44
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